Driving Discovery, Improving Lives

At UC Irvine, discovery is just the beginning. Our researchers are reimagining what is possible, from developing new Alzheimer’s treatments to pioneering AI breakthroughs. But innovation does not happen in isolation. It requires collaboration, infrastructure and sustained support. With critical funding, we can continue to drive progress that matters to you and our shared future.

See Reseach in Action

Driving Discovery, Improving Lives

At UC Irvine, discovery is just the beginning. Our researchers are reimagining what is possible, from developing new Alzheimer’s treatments to pioneering AI breakthroughs. But innovation does not happen in isolation. It requires collaboration, infrastructure and sustained support. With critical funding, we can continue to drive progress that matters to you and our shared future.

See Reseach in Action

By the Numbers

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Research fuels what's next. Its impact can be measured in lives improved, economies strengthened and communities transformed.

$8.1 billion annual economic impact across California

4 million patients served in Orange, Los Angeles, San Bernardino and Riverside counties

$46.2 billion in investments in and returns from UC Irvine startups

Revolutionizing Brain Health

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Our research is advancing early detection and innovative care, improving patient outcomes while reducing healthcare costs and creating economic impact.

Michael Yassa, right, with co-authors Bryce Mander and Destiny Berisha

NATIONAL INSTITUTE OF AGING

Linking sleep apnea during REM sleep to memory loss, brain changes

UC Irvine researchers find that low oxygen levels may injure critical cerebral regions

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UC Irvine professors Mathew Blurton-Jones (left) and Robert Spitale

NATIONAL INSTITUTE OF AGING

Engineering a new way for treating Alzheimer’s and other brain diseases

UC Irvine team develops cell-based platform for brain-wide delivery of therapeutic agents

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Dr. Tallie Z. Baram

NATIONAL INSTITUTE OF MENTAL HEALTH

Understanding how early-life adversity shapes the brain and behavior

Review study has important implications for early intervention, prevention strategies

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Stock illustration of nasal cavity

PROCTOR AND GAMBLE

Unlocking memory through the power of scent

Researchers discover that scent exposure during sleep may significantly boost memory and protect brain health in older adults

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Technology That Transforms

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From artificial intelligence to quantum science, we are developing smarter systems, cleaner energy and a more connected world.

Bill Tomlinson

NATIONAL SCIENCE FOUNDATION

Advancing AI for sustainability education

UC Irvine researchers earn a $900,000 NSF grant to develop AI-driven, personalized learning in sustainability science

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left to right: Padhraic Smyth and Mark Steyvers

NATIONAL SCIENCE FOUNDATION

Developing a hybrid human-machine framework for building smarter AI

Model uses human and algorithmic predictions and confidence scores to boost accuracy

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left to right: Toshiki Tajima and Michl Binderbauer

DEPARTMENT OF ENERGY

Approaching the goal of fusion power

Born at UC Irvine, fusion technology moves closer to powering the world

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Advancing Medical Frontiers

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We are reimagining healthcare to address critical health challenges affecting millions worldwide.

Left to right: Raul Ramos and Maksim Plikus

NATIONAL INSTITUTES OF HEALTH NATIONAL SCIENCE FOUNDATION

Advancing regenerative medicine treatments using fats from cartilage

The fat-rich, stress-resistant tissue could transform treatment for facial injuries, birth defects and cartilage disease

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Elizabeth Bess of the Department of Chemistry

NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

Tracing Parkinson’s disease origins to gut bacteria

Researchers identify how gut bacteria may trigger the disease, uncovering potential ways to stop it before it starts

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UC Irvine Susan Samueli Integrative Health Institute

NATIONAL INSTITUTES OF HEALTH

Leading the way in integrative health

UCI Health advances the future of healthcare with an interdisciplinary, evidence-based approach to health and wellness

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Implant that measures neurological signals in patients' developing brains seen on butterfly's wing

NATIONAL INSTITUTES OF HEALTH NATIONAL SCIENCE FOUNDATION

Monitoring brain development using bioelectric sensors

Engineered to move with the body, this flexible implant enables safer brain monitoring in children as they grow

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Safeguarding Our Future

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Our researchers are enhancing cybersecurity and strengthening national defense capabilities.

Yoonjin Won

DEPARTMENT OF DEFENSE

Thermal energy innovation to drive next-gen Navy energy and power systems

Department of Defense-funded initiative aims to apply machine learning to transform heat management in critical defense infrastructure

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Payam Heydari

DEPARTMENT OF DEFENSE

Academic-industry alliance to drive innovation in 5G/6G and next-gen U.S. manufacturing

As part of the California Defense Ready Electronics and Microdevices Superhub, UC Irvine will help accelerate domestic innovation and manufacturing

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Mantis shrimp

AIR FORCE OFFICE OF SCIENTIFIC RESEARCH

Mantis shrimp research offers insight into impact-resistant materials for engineering use

Findings could lead to stronger protective equipment for cars, aerospace and defense

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Pioneering Sustainable Solutions

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From clean energy breakthroughs to resilient urban design, we are creating a healthier planet and spurring economic growth through green innovation.

Comparison depicts CA's eroding beaches over time

NATIONAL SCIENCE FOUNDATION, NOAA, NASA

Saving California’s eroding beaches

Multi-prong effort can preserve our coastlines to protect housing and infrastructure

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Mo Li, UC Irvine professor of civil and environmental engineering as well as materials science and engineering

CALIFORNIA ENERGY COMMISSION

Making wind power more practical

Campus lab pioneers 3D-printed concrete components to produce massive turbines for clean energy

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Sunny Jiang, UC Irvine professor of both civil and environmental engineering and ecology and evolutionary biology

NATIONAL SCIENCE FOUNDATION, ENVIRONMENTAL PROTECTION AGENCY

Making our coastal waters healthier

Engineering research finds balance between human activities and coastal ecosystems

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Huolin Xin, UCI professor of physics & astronomy

DEPARTMENT OF ENERGY

Reinventing how lithium batteries are recycled

Department of Energy-funded project makes these power sources more sustainable

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Federally Funded Research Centers

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UC Irvine is home to federally funded research centers tackling some of the most urgent health, scientific and technology challenges of our time. From cancer cures to advanced materials, these nationally recognized hubs advance discovery, improve health and bring critical funding to Orange County.

Advancing the best in cancer research and care

Chao Family Comprehensive Cancer Center is OC’s only National Cancer Institute-designated center

Visit center

Unlocking the mystery of Alzheimer’s disease

UCI MIND is one of the few research U.S. centers designed by the National Institute of Aging

Visit UCI MIND

Translating research into new cures

NIH-supported Institute for Clinical & Translational Science moves science from ‘lab to life’

Visit institute

Researcher observing cells

Ushering in a new era of biology

NSF and Simons support advanced research about the building blocks of life in the Center for Multiscale Cell Fate Research

Visit center

UC Irvine Engineering building

Solving critical challenges with unique materials

The Center for Complex and Active Materials is one of 20 National Science Foundation Materials Research Science and Engineering Centers

Visit center

Researchers in a microfluidics lab

Providing health and environmental solutions

NSF-industry-supported Center for Advanced Design and Manufacturing of Integrated Microfluidics helps companies address technical challenges.

Visit center

Speak Up for Science:

Your Voice Matters

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Scientific discovery improves lives and drives innovation that benefits everyone. Your voice can help ensure continued investment in research that impacts your health, advances technology and shapes our future. Urge your representatives to protect funding for research – including life-saving medical breakthroughs, technological solutions that enhance quality of life and economic growth through innovation.

Support progress for all. Support impactful innovation. Support UC Irvine research.

Email Your Representative

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